Amaurosis fugax

Amaurosis fugax in young adults.

EDITOR,-We read with interest the article by O'Sullivan et al.' The nine presented patients went through extensive investigations, including echocardiograms in all cases. Yet, no evidence of an embolic or atheromatous aetiology was found. Unfortunately, the authors failed to mention whether the echocardiography was transthoracic or transoesophageal. We had experience with a 29-year-old woman, w...

Amaurosis fugax: a clinical comparison.

Amaurosis fugax (transient monocular blindness) is a symptom of retinal ischemia just as contralateral hemiparesis and sensory loss are symptoms of cerebral ischemia. These symptoms are produced by atherosclerotic stenosis of the carotid vessels at the ipsilateral carotid bifurcation and emboli from these areas causing focal, repetitive, retinal ischemia. A study of 31 endarterectomy patients w...

Amaurosis fugax in young people.

Nine young adults (median age 19.5 years) who suffered from amaurosis fugax (AF) are described. The attacks of AF were short in duration and preceded by premonitory symptoms in five cases and by a migrainous headache in two. In five patients the visual loss progressed in a lacunar pattern unlike the 'curtain' pattern characteristic of AF in older patients. Investigation revealed no evidence of ...

The natural history of amaurosis fugax.

Novel mouse model of monocular amaurosis fugax.

BACKGROUND AND PURPOSE Retinal ischemia is a major cause of visual impairment and is associated with a high risk of subsequent ischemic stroke. The retina and its projections are easily accessible for experimental procedures and functional evaluation. We created and characterized a mouse model of global and transient retinal ischemia and provide a comprehensive chronologic profile of some genes...